Sql Server 2000 & Vb.net Connection Problem

Hi,

I am new for VB.net and I have defined the connectionstrings in
web.config.

<appSettings>
<add key="constring"
value="Data Source=Localhost;Initial Catalog=nexus;user
id=nexusdb;password=nexus123;Integrated Security=SSPI;workstation
id=localhost;packet size=4096;Persist securityinfo=False;Trusted
Connection=Yes">
</add>
</appSettings>

while i am trying to connect with sql server 2000 ,
it shows me

Login failed for user 'nexusdb'.

Exception Details: System.Data.SqlClient.SqlException: Login failed
for user 'nexusdb'.

Pls tell me what should I do to access Database.

anand